ABSTRACT
Psoriasis is an unremitting, inflammatory, autoimmune disorder of the skin disease. It is characterized by excessive growth and aberrant differentiation of keratinocytes. Although psoriasis occurs worldwide is 2-5%. The study found that 35% of people have moderate to severe psoriasis. Several approaches have been explored by researchers with different anti-psoriasis drugs for their successful treatment. But psoriasis is a challenge to treat due to its chronic recurring nature and lack of a perfect carrier for safe and effective delivery of antipsoriatic drugs. Novel nanocarriers have been thoroughly investigated like liposomes, transferosomes, niosomes, ethosomes, SLN, NLC, microspheres, micelles, nanocapsules, dendrimers, etc. Presently nanocarriers have gained widespread application for effective and safe treatment of psoriasis. The present review focuses on currently existing treatment options and recent developments in the delivery of various antipsoriatic drugs through revolutionary nano carriers categorized as lipid-based carriers and polymer-based carriers.
Keywords: Psoriasis, Nanocarriers, Liposome, Antipsoriatic drugs, Nanoparticle.