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Yahya Khan*, Sahera Nasreen

P.G. Department of Botany, Government Institute of Science and Research Center, Nipat Niranjan Nagar, Caves Road, Aurangabad-431004, MS, India.

ORIGINAL RESEARCH ARTICLE
ARTICLE INFORMATION

Article history
Received: 08 December 2013
Revised: 17 December 2013
Accepted: 22 December 2013
Early view: 30 December 2013

*Author for correspondence
E-mail: yahyakhan28@gmail.com

Keywords:
Antioxidants
DPPH
TLC
Free radical.

ABSTRACT

Objectives: India has a rich in medicinal herbs and spices, which includes about more than 2000 species and has a vast geographical area with high potential abilities for Ayurvedic, Unani, Siddha traditional medicines but only very few have been studied chemically and pharmacologically for their potential medicinal value. The aim of the present study to investigate the antioxidant constituents from the natural source from the leaves of Santalum album.
Materials and methods: Attempts were also made to extract phenolic antioxidant using aqueous and methanolic extracts were screened for antioxidant activity. The Antioxidant activity of constituents in aqueous and methanol extract was evaluated by DPPH free radical scavenging activity.
Results: Pre-treatment of test animals with Hemidesmus indicus (75 & 100 mg/kg i.p) reduced the catalepsy score in haloperidol treated mice. Both the doses i.e. 75 & 100 mg/kg (i.p.) of Hemidesmus indicus showed protective effects against haloperidol-induced catalepsy.
Conclusion: Santlum album is potent source of antioxidants further research is needed to isolate antioxidant from it.