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Mohammad Mansoor, Cheelapogu Venkateswarlu*, Srinivasa Rao D.

K.C. Reddy Institute of Pharmaceutical Sciences, Guntur, Andhra Pradesh-522 348, India.

ORIGINAL RESEARCH ARTICLE
Volume 3, Issue 2, Page 84-88, May-August 2015.

Article history
Received: 15 July 2015
Revised: 8 August 2015
Accepted: 10 August 2015
Early view: 13 August 2015

*Author for correspondence
E-mail: venku07177@gmail.com

ABSTRACT
Background: The present study was designed to investigate the antiulcer potential of ethanolic leaves extract of Cajanus cajan.
Material and methods: Antiulcer activity was evaluated by pylorus ligation induced ulcer models in rats. The ethanolic extract of the leaves of Cajanus cajan was given by oral route at a dose of 250 and 500mg/kg b.w.
Results: Ethanolic extract of Cajanus cajan, dose dependently reduce, the total acidity, ulcer index, and an increase in pH of gastric juice in pylorus ligated ulcer model.
Conclusion: Extract of Cajanus cajan may be useful as a natural antioxidant in the treatment of ulcer.
Keywords: Antiulcer Activity, Cajanus cajan, Pylorus ligation ethanolic extract.