Suhail Ahmad1*, Mohd. Wajeehul Qamar2, Mohammad Zaki Ahmad3, KM Yusuf Amin4, JA Ansari5.
1Department of Ilmul Saidala, Sufia Unani Medical College, Hospital & Research Centre, East Champaran, Bihar, India.
2Department of Ilmul Advia, Sufia Unani Medical College Hospital and Research Centre, East Champaran, Bihar, India.
3 Department of Ilaj Bit Tadbeer, Sufia Unani Medical College Hospital and Research Centre, East Champaran, Bihar, India.
4Department of Ilmul Advia, Aligarh Muslim University, Aligarh, U.P. India.
5Department of Pharmacy Practice, Faculty of Pharmacy, Integral University, Lucknow, India.
ORIGINAL RESEARCH ARTICLE
Volume 10, Issue 3, Page 101-109.
*Author for correspondence
E-mail: suhailfarqaleet@gmail.com
ABSTRACT
Aim: Bisehri booti (Aerva lanata) is an effective traditional medicine used for the treatment of various disorders. This study aimed to investigate the anti-inflammatory, analgesic and steroidal activities in albino rats.
Material and Methods: Four groups of five animals each were administered normal saline, hydrochlorothiazide, aqueous extract of Bisehri booti, and juice of Bisehri booti, respectively. Different test is used to asses these activities such as Carrageenin-Induced Rat Paw Oedema Test, Eddy’s Hot Plate Test and Analgesiometer Test etc.
Results: The aqueous extract and juice of A. lanata significantly reduced inflammation in animals treated with 15mg/100g and 20mg/100g of extract and juice, respectively. The test drug did not produce a significant increase in reaction time during the entire testing period for analgesic activity. The thymus/body weight values were significantly reduced in all test groups, with the juice being more effective than the aqueous extract.
Conclusion: The study demonstrates that A. lanata (Bisehri booti) has noteworthy anti-inflammatory and steroidal properties, which validates its traditional use for these activities in Tibb-e-Unani. This research establishes the foundation for promoting the drug from the side-lines to the forefront of the medical field, thereby propelling the advancement of the Unani system of medicine.
Keywords: Bisehri booti, Aerva lanata, Anti-inflammatory, Analgesic, Steroidal Activity, Aqueous Extract.
Aim: Bisehri booti (Aerva lanata) is an effective traditional medicine used for the treatment of various disorders. This study aimed to investigate the anti-inflammatory, analgesic and steroidal activities in albino rats.
Material and Methods: Four groups of five animals each were administered normal saline, hydrochlorothiazide, aqueous extract of Bisehri booti, and juice of Bisehri booti, respectively. Different test is used to asses these activities such as Carrageenin-Induced Rat Paw Oedema Test, Eddy’s Hot Plate Test and Analgesiometer Test etc.
Results: The aqueous extract and juice of A. lanata significantly reduced inflammation in animals treated with 15mg/100g and 20mg/100g of extract and juice, respectively. The test drug did not produce a significant increase in reaction time during the entire testing period for analgesic activity. The thymus/body weight values were significantly reduced in all test groups, with the juice being more effective than the aqueous extract.
Conclusion: The study demonstrates that A. lanata (Bisehri booti) has noteworthy anti-inflammatory and steroidal properties, which validates its traditional use for these activities in Tibb-e-Unani. This research establishes the foundation for promoting the drug from the side-lines to the forefront of the medical field, thereby propelling the advancement of the Unani system of medicine.
Keywords: Bisehri booti, Aerva lanata, Anti-inflammatory, Analgesic, Steroidal Activity, Aqueous Extract.
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