Mahfooz ur Rahman1*, JA Ansari2, H Kabir1, M Asif1.
1Department of Ilmul-Advia, Faculty of Medicine (Unani), Jamia Hamdard, New Delhi, INDIA.
2Department of Pharmacology, MESCO College of Pharmacy, Hyderabad, Telangana, INDIA.
ORIGINAL RESEARCH ARTICLE
Volume 9, Issue 3, Page 76-82.
*Author for correspondence
E-mail: mahfoozjh@gmail.com
ABSTRACT
Background: The medicinal plant Caesalpinia bonducella (CBC; Karanjwa) is widely spread in India’s coastal region, Burma, Sri Lanka, and other tropical and subtropical regions of the world. The goal of this study was to see if Caesalpinia bonducella had analgesic and anti-inflammatory properties in laboratory animals.
Materials and Methods: Acetic acid-induced abdominal writhing and a hot plate test were used to assess analgesic efficacy in rats at doses of 7, 10.50, and 14 mg/kg. Carrageenan was used to assess anti-inflammatory properties in rats.
Results: There was a significant reduction in the number of writhing in 20 minutes observed. There was a significant increase in the reaction time observed for 30 min, 60 min, and 90 min. A significant reduction in the paw volume was observed at Ist, 3rd, and 5th hr.
Conclusion: Caesalpinia bonducella was found to have strong analgesic and anti-inflammatory action in rats, according to the findings.
Keywords: Karanjwa, Pain, Inflammation.
Background: The medicinal plant Caesalpinia bonducella (CBC; Karanjwa) is widely spread in India’s coastal region, Burma, Sri Lanka, and other tropical and subtropical regions of the world. The goal of this study was to see if Caesalpinia bonducella had analgesic and anti-inflammatory properties in laboratory animals.
Materials and Methods: Acetic acid-induced abdominal writhing and a hot plate test were used to assess analgesic efficacy in rats at doses of 7, 10.50, and 14 mg/kg. Carrageenan was used to assess anti-inflammatory properties in rats.
Results: There was a significant reduction in the number of writhing in 20 minutes observed. There was a significant increase in the reaction time observed for 30 min, 60 min, and 90 min. A significant reduction in the paw volume was observed at Ist, 3rd, and 5th hr.
Conclusion: Caesalpinia bonducella was found to have strong analgesic and anti-inflammatory action in rats, according to the findings.
Keywords: Karanjwa, Pain, Inflammation.
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